Different hair loss types (e.g., androgenetic alopecia, scarring alopecia, telogen effluvium) affect different parts of this structure.
Understanding the hair cycle, hair function, and anatomy is essential when receiving treatment for hair loss. It ensures that therapies are accurately targeted, respect the natural roles of hair, and support healthy regrowth without causing unintended damage. Without this knowledge, treatments may be ineffective or even harmful, leading to poor outcomes.
Basic hair science includes histology, anatomy, function, biochemistry, and the hair cycle. We will try to explain all these in a comprehensive way.
The bulge in the middle of the hair follicle contains stem cells. It is the most important part in follicle growth and regeneration. During hair transplant this segment of the graft must be well preserved. In FUE, when too small a punch is used, the extracted follicle may deprived of bulge tissue. In “Hair Cloning”, the dermal sheath of the follicle is cultured in medium.
The multiplied tissue is then injected into the skin to induce new hair formation. The stem cells in the bulge is multi-purposes. Hair follicle transplant had shown to return skin color in a skin disease called “vitiligo”. The average healthy hair fiber diameter is 0.08mm or over. Below 0.04mm the hair fibers are too thin to achieve visual coverage of the scalp
Many treatments are being developed to stimulate the stem cells: new hair follicles can be formed; even white hairs can turn black. 5 α reductase converts testosterone into DHT. This enzyme is located in the Sebaceous Glands.
Dr Inaba (Japan) believes that over consumption of animal fat swells the sebaceous gland, increases the amount 5 α reductase and DHT, leading to earlier onset of androgenetic hair loss.
Laser is able to stimulate and preserve hair follicles in patients with androgenetic alopecia and other hair loss disorders. Laser has been used over the past few years in a number of laser devices (combs, caps, hairdryer-like) for treatment of genetic or acquired hair loss. The Laser energy addresses hair loss at the hair follicle cellular level, rejuvenating miniaturizing hair follicles in seven major ways:
Hair transplants can initially traumatize the scalp and can result in a temporary hair loss during the first 4 months (this is known as shock loss). Some patients may experience swelling in the transplanted area. The transplanted donor follicles can also experience difficulty adapting to their new environment. Clinical studies have demonstrated the following beneficial effects of laser when use in conjunction with hair transplant.
• minimizes hair shedding (shock loss)
• strengthen hair follicles after surgery with a much higher probability of survival
• reduce swelling, redness and inflammation post-surgery
Laser hair therapy stimulates the mitochondria in cells to increase the production of adenosine triphosphate (ATP). ATP is the form of energy used by hair cells to grow imto follicles. Abundant energy supply is critical when dealing with weakened and traumatized hair follicles.
Laser hair therapy devices have been used by thousands of hair transplant centers all over the world (such as Bosley and HairClub). However handheld contraptions made with cheap Light Emitting Diodes (LEDs) are worthless when it comes to energizing the base of hair follicles. Technologically advanced device with the FDA-cleared is now available in our center for use after hair transplant. A 20 minutes of treatment is able to revive the mitochondria of hair cells. This can result in stronger hair follicles with a higher probability of surviving the operation. These extra amounts of “survivor” hair grafts will eventually grow into healthy, terminal hairs.
Since the first experiments in the 1960s with laser treatment for impaired wound healing, there has been much research-both lab-based and clinically-into the use of lasers for medical treatment. Later Nils Finsen pioneered the use of UV therapy for which he won the Nobel prize in 1904 [2]). The use of lasers and LEDs as light sources was the next step in the technological development of light therapy, which is now applied to many thousands of people worldwide each day.
The Lasers and LEDs are applied directly to the respective areas (e.g., wounds, sites of injuries) or to various points on the body (acupuncture points, muscle-trigger points). Controlled clinical trials have shown efficacy in treating stroke, stimulating wound healing, orthopedic conditions and relief of chronic inflammation. Preclinical studies have shown effectiveness in spinal cord injuries, peripheral nerve regeneration, heart attacks, degenerative brain diseases and traumatic brain injury.
Human hairs do not grow all the time, but in phases or returning cycles. Different hairs would have different cycle. During a human life, the growth cycle of a scalp hair will repeat itself on average 20 times from birth on. Scalp hair cycle consists of 5 phases:
Laser Therapy, also referred to as Low Level Laser Therapy (LLLT), cold laser therapy, photobiomodulation, biostimulation, and phototherapy, has been shown in thousands of peer-reviewed publications to increase cellular survival, proliferation and function. The laser light after absorbed by mitochondria in the cell produces the following actions
The question is no longer whether light has biological effects but rather how energy from therapeutic lasers and LEDs works at the cellular and organism levels and what the optimal light parameters are for different uses of these light sources.
One important point that has been demonstrated by multiple studies in cell culture, animal models and in clinical studies is the concept of a biphasic dose response with the total delivered light energy density (fluence).
The reason why the technique is termed Low-level is that there exists an optimal dose of light for any particular application, and dose lower than this optimum value, or more significantly, larger than the optimum value will have a diminished therapeutic outcome, or for high doses of light a negative outcome may result.
The methods for delivering the therapeutic light are diverse. The field is characterized by a variety of methodologies and uses of various light sources (lasers, LEDs) with different parameters (wavelength, output power, continuous-wave or pulsed operation modes, pulse parameters, polarization state etc). In 2002 MicroLight Corp received 510K FDA clearance for the ML 830-nm diode laser for treatment of carpal tunnel syndrome.
There were several controlled trials reporting significant improvement in pain and some improvement in objective outcome measures. Since then several light sources have been approved as equivalent to an infra-red heating lamp for treating a wide-range of musculoskeletal disorders with no supporting clinical studies.
The methods for delivering the therapeutic light are diverse. The field is characterized by a variety of methodologies and uses of various light sources (lasers, LEDs) with different parameters (wavelength, output power, continuous-wave or pulsed operation modes, pulse parameters, polarization state etc). In 2002 MicroLight Corp received 510K FDA clearance for the ML 830-nm diode laser for treatment of carpal tunnel syndrome.
There were several controlled trials reporting significant improvement in pain and some improvement in objective outcome measures. Since then several light sources have been approved as equivalent to an infra-red heating lamp for treating a wide-range of musculoskeletal disorders with no supporting clinical studies.
The methods for delivering the therapeutic light are diverse. The field is characterized by a variety of methodologies and uses of various light sources (lasers, LEDs) with different parameters (wavelength, output power, continuous-wave or pulsed operation modes, pulse parameters, polarization state etc). In 2002 MicroLight Corp received 510K FDA clearance for the ML 830-nm diode laser for treatment of carpal tunnel syndrome.
There were several controlled trials reporting significant improvement in pain and some improvement in objective outcome measures. Since then several light sources have been approved as equivalent to an infra-red heating lamp for treating a wide-range of musculoskeletal disorders with no supporting clinical studies.
Component | Content % | Remarks |
---|---|---|
Keratin | 80%-90% | • Formed from dead protein • Contains 20 kinds of amino acids• Provide strength for the shaft |
Water | 10%-30% | Provide shaft elasticity |
Lipid ( Fat ) | 10% | |
Trace Elements | Very small Quantity | Zinc, Mercury, Cobalt, Iron, Selenium … |
Melanin | — | Accounts for hair color |
Hair root, alsp known as Dermal Papilla, is a tunnel-like segment of the epidermis that extends down into the dermis. It can be divided into 2 compartments :
Protect and form the growing hair shaft. Also service as source of energy for protein synthesis during hair growth. Cells found in ORS are :
Consists of 3 layers :
The tissue surrounding the hair root is known as Adventitous Tissue. It is consisted of several components:
A muscle attaches the bulge to the skin. When this muscle contracts, it causes the hair to stand up which also causes the sebaceous gland to secrete oil. This muscle must be cut in FUE to extract the follicle.
Contain melanosomes and synthesize melanins which account for the pigmentation of hair and skin.
Opens into the isthmus. This gland secretes sebum, a semi-fluid secretion consisting chiefly of fat, keratin, and cellular material. The sebum lubricates shaft and carries away debris generated in the follicle.
Scientists have discovered that stem cells are plentiful in the fat tissue, the so called Adiposed Stem Cells (ASC). ASC has been used in cardiovascular and cosmetic surgery to generate new tissues.
% growth after 19 months |
Skinny Graft |
Chubby Graft |
---|---|---|
2-hair follicular units | 69.3 % | 88.0 % |
1-hair follicular Units | 48 % | 98 % |
From consultation, surgery, to aftercare, you will receive continued personal care by our doctors, not just consultants.
Have a question? Please feel free to call our friendly customer service.
International Accreditations
Recognized by leading global medical bodies, our clinic stands as one of the most qualified and internationally accredited hair transplant centers in Hong Kong and mainland China. We are proud to uphold the highest standards in medical ethics, safety, and surgical expertise.
Hair transplant is the ultimate solution to restores hair, but not everyone is good candidate.
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Location : 6/F 29 Austin Road, Tsimshatsui, Kowloon, Hong Kong